The most potent SIRT1 activator for your formulas!
The benefits of polyphenols as antioxidants, cardiovascular protectors, etc., have been known for years, but their practical use was limited by their low bioavailability… until now!
What is Pterovita® for food?
Pterovita® is a patented bioactive crystalline formula consisting of pterostilbene (nature’s best SIRT1 activator and the most powerful antioxidant polyphenol) and picolinic acid (a human endogenous compound with neuroprotective properties).
Polyphenols are nature’s gift for health, offering antioxidant protection, cardiovascular support, anti-inflammatory action, metabolic regulation, neuroprotective action, microbiota improvement, and more. Pterostilbene is the most promising and beneficial, but its low bioavailability has held it back… until now!
CIRCE Scientific has developed a formula that facilitates pterostilbene’s fast and complete dissolution and absorption, providing at last the needed concentration to trigger its promising health benefits shown in studies.
A pterostilbene that works
Key benefits Pterovita®
Enhanced bioavailability
Increases pterostilbene bioavailability by 4-fold compared to regular formulations.
Faster absorption
Reduces the time to reach maximum blood concentration (Tmax) from 6 hours to just 1 hour and 20 minutes.
Increased peak concentration
Delivers a 7.5-fold higher Cmax, crucial for triggering biological responses.
SIRT1 activation
More effectively activates SIRT1, the enzyme linked to longevity, cellular repair, and stress resistance.
Potent antioxidant properties
Beyond neutralizing free radicals like other normal antioxidants, Pterovita® enhances the body’s natural antioxidant defenses through Nrf2 activation.
Inflammation management
Helps reduce inflammation by downregulating NF-kB, a key inflammatory signal molecule.
Supports healthy aging
Contributes to cellular function, neuroprotection, cardiovascular health, and metabolic regulation.
Anti-aging
May support cellular function and contribute to slowing the aging process.
Anti-inflammatory
Could help alleviate inflammation and encourage natural healing.
Neuroprotective
Supports brain cell health and may promote cognitive well-being.
Sports performance
Assists in improving recovery after physical activity.
Beauty from within
Contributes to radiant and healthy skin by nourishing cells from the inside out.
Activates antioxidant system
May enhance the body's natural antioxidant defenses to protect against damage.
Regulates in cardiovascular health and diabetes
Could help regulate blood sugar levels and promote cardiovascular wellness.
Enhanced bioavailability in humans
Pterovita® has shown a 4x increase in pterostilbene’s bioavailability compared to its original form. Not only that, but it also affords a higher peak (Cmax) of crucial importance to trigger the biological pathways.
Nature’s most potent SIRT1 activator
Pterovita® unlocks pterostilbene’s full potential as nature’s best SIRT1 activator, surpassing resveratrol by far. SIRT1 is a key regulator of cell defense and survival in response to stress, involved with diverse biological functions including cell development, metabolism, DNA repair, apoptosis, and longevity.
Beyond antioxidants
Pterovita® doesn’t just neutralize free radicals; it can help empower your body’s own antioxidant defenses through Nrf2 activation, generating its own antioxidants. This proactive approach provides comprehensive protection against oxidative stress.
Activates the antioxidant defenses of cells
Pterovita® can help cells downregulate NF-kB, a complex understood as the command-and-control center when it comes to inflammation in the body.
How can Pterovita® be used?
Supplements
Bakery
Bars
Beverages
Gummies
Formulating with Pterovita®
- In its raw state, Pterovita® is a slightly yellow powder. No noticeable smell and a slightly bitter, spicy flavor.
- High temperature and pressure procedures to incorporate Pterovita® in food didn’t affect its stability.
- The enhanced solubility of Pterovita® results in a 4-fold increase in AUC and a 7.5-fold increase in Cmax.
- Pterovita® has been shown to be stable as a solid for at least 30 months at long term conditions (25° C/77°F± 2° C and 60± 5% humidity). The stability test is still ongoing, and retest time expected to increase.
- Pterovita® is proven to be non-toxic, with 14 days of comprehensive toxicity studies at various doses and NOAEL established at 300 mg/kg/day.
- Pterovita® is manufactured in a cGMP, HACCP, Halal certified plant.
- Pterovita® has been granted Generally Recognized as Safe (GRAS) status by an independent expert panel, who established a 220 mg/day ADI (for a 60 kg adult).
Approved
Self-affirmed GRAS by Expert Panel according to FDA Guidelines
Human Tested Product
Human-tested high bioavailability
High Quality Product
Produced under cGMP
Produced under HACCP
Halal Certified
Tested in Europe
Safe Product and Certifications
Gluten Free
Allergens free
Banned substances-free
Aflatoxin free
Pesticide Free
Melamine Free
PCB Free
Nanomaterial tech. free
Non-GMO
Brochure Pterovita®
Download the brochure and access all the summarized information about Pterovita® for Food. Get a complete overview of how we can help you achieve your goals.
