Unlocks the full health benefits of Pterostilbene
Longevity has long been a captivating topic for humanity, driving the quest for ways to extend life and, crucially, enhance healthspan. Anti-aging products offer promises of combatting visible signs of aging and promoting cellular health. Yet, not all products are created equal; many lack robust scientific evidence to substantiate their claims. At CIRCE, we understand the importance of scientifically-backed solutions. Our products are meticulously formulated to not only address the visible signs of aging but also to support cellular health, offering a path to prolonged vitality and well-being.
? An effective product in health and longevity isn’t just about providing one benefit; it’s about addressing all 12 signs of aging simultaneously. The components of Pterovita have undergone years of scientific research, with over 600 published articles supporting their beneficial effects on these indicators, demonstrating it as a powerful ally in promoting longevity. Furthermore, through the innovation of co-crystal technology, its efficacy has been enhanced, achieving unprecedented bioavailability. This translates to greater utilization by organisms, making it an even more effective option for improving health and well-being as we age.
SOLUBILITY
DISSOLUTION
BIOAVAILABILITY
PTEROVITA addresses each of the 12 hallmarks of aging
Through its innovative formulation and scientifically-backed ingredients, it targets multiple aspects of aging, promoting cellular health and longevity.
Genomic Instability: Repairs and strongly protects cells from DNA
damage by increasing the production of sirtuins (especially Sirt1, Sirt2,
and Sirt3) and other mechanisms.
Telomere Attrition: By increasing cell vitality and proper functioning,
cell divisions are less frequent, thus preventing telomere shortening.
Epigenetic Alterations: Reduces the occurrence of epigenetic alterations as a
potent antioxidant.
Loss of Proteostasis: Maintains the balance and regulation of proteins
within cells through its antioxidant power, improvement of
mitochondrial function, and mTOR regulation.
Disabled Macroautophagy: Regulates mTOR expression,
the main enzyme that prevents the necessary autophagy process.
Deregulated Nutrient-Sensing: Regulates genes related to nutrient
metabolism, including glucose metabolism.
Mitochondrial Dysfunction: Revitalizes cells by promoting mitochondrial
biogenesis and contributes to their proper functioning through its
antioxidant power.
Cellular Senescence: Controls multiple factors triggering cell death,
such as oxidative environment, DNA damage, toxic protein
expression, among others.
Stem Cell Exhaustion: Decreases factors causing cell death,
thus preventing the depletion of cells like stem cells.
Altered Intercellular Communication: Maintains proper neuronal
communication and the connection between the gut-brain axis.
Chronic Inflammation: Regulates key genes substantially favoring
the reduction of inflammatory processes.
Dysbiosis: Prevents the deterioration of the intestinal microbiota,
improving its composition and function.
A Source of Unparalleled Vitality
20mg/kg of PTEROVITA, which contains 68% pterostilbene, achieves 9.9 times higher levels in the blood (measured as pterostilbene AUC/dose) than 20mg/kg of regular pterostilbene.
This results in improved activity and significant dose reduction (a 1/8th dose is sufficient to achieve equivalent blood levels due to non-linear pharmacokinetics).
In internal studies, Pterovita demonstrated significantly more effective absorption by the body compared to similar commercial products, resulting in better outcomes upon consumption.
PTEROVITA combines Pterostilbene and Picolinic acid in a patented cocrystal, leveraging their synergistic effects to maximize the bioavailability of Pterostilbene, unlocking the full range of longevity benefits from both compounds.
A cocrystal is a new crystalline form that combines two or more different molecules to create a structure with improved physicochemical properties compared to the individual components.
Picolinic Acid
The body naturally produces picolinic acid, also ingested through diet, as a derivative of the amino acid tryptophan. It plays a vital role in the absorption and metabolism of essential oligonucleotides like zinc and has proven efficacy in neurodegenerative diseases and as an antimicrobial agent.
Pterostilbene
Pterostilbene, a naturally occurring compound from the stilbene group, is predominantly found in blueberries. Its proven efficacy in combating the 12 signs of aging is well-established. Additionally, it stands out for its ability to activate sirtuins, enzymes associated with longevity.
Pterostilbene and picolinic acid are two compounds that have been studied for their potential health benefits. PTEROVITA, with its unique cocrystal combination, maximizes their synergistic effects, unlocking the full potential of their natural health benefits.
Pterostilbene
Analgesic effects: may modulate pain receptors or reduce inflammation in the body.
Longevity & health-span support: may reduce oxidative stress and help slow down the aging process.
Anti-diabetic effects: May help blood sugar regulation & diabetes management: may help regulate blood sugar levels.
Neuroprotective effects: may help protect the brain from damage and degeneration.
Anti-inflammatory effects: may help reduce inflammation in the body.
Anti-hypertensive effects: may help lower blood pressure.
Antioxidant effects: may help protect cells from damage caused by free radicals.
Picolinic Acid
Mineral absorption: help improve their absorption in the body
Osteoporosis prevention: may help prevent osteoporosis by enhancing the absorption and utilization of calcium in the body
Immune system support: may enhance the immune system's response to certain infections.
NAD Production: plays a significant role in the metabolic pathways leading to the production of NAD in the brain.
Anti-inflammatory effects: may help reduce inflammation in the body.
Antioxidant effects: may help protect cells from damage caused by free radicals.
Synergies in support of health and longevity
Given that longevity is achieved by simultaneously addressing all signs of aging, product development must also be aligned with combinations that allow unbeatable synergies. That’s why key ingredients have been incorporated into the Pterovita formula: the natural flavonoid silibinin and an NAD+ booster.
Silibinin is a natural compound derived from milk thistle, widely known for its hepatoprotective and antioxidant properties.
Meanwhile, NAD+ (nicotinamide adenine dinucleotide) is an essential coenzyme involved in many important biochemical reactions in cells. It is crucial for energy production, carbohydrate and fat metabolism, and DNA repair.
Combining Pterovita with these compounds offers a comprehensive approach to supporting longevity, generating synergy that provides additional health benefits, highlighting its powerful DNA repair ability, especially against UV and ionizing radiation, providing robust additional support for preventing premature aging and maintaining long-term health.
*These described effects have not been evaluated or validated by FDA, EFSA or any other competent authority. This product is not intended to cure, prevent, diagnose or treat any disease.
PTEROVITA has been granted Generally Recognized as Safe (GRAS) status by an independent expert panel, which verifies its safety and quality control measures. PTEROVITA’s unique market position is further strengthened by its third-party quality control and Good Manufacturing Practice (GMP) production. Our ingredient can be broadly used as it is Non-GMO, Halal, Gluten-Free, and suitable for Vegans (as defined by the European Vegetarian Union).
GMP
Non-GMO
Halal
Gluten Free
Suitable
for Vegans
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